22 Oct 1941
- An explosion at the Romanian Command Headquarters in Odessa, Ukraine killed 67, including Romanian General Glogojeanu and four German Navy officers. The explosion was caused by a time-delayed bomb left by Soviet Coastal Army personnel during the evacuation. Antonescu ordered 100 Jews and Communists would die for each enlisted man and 300 for each officer killed in this explosion. ww2dbase [CPC]
- The assassination of Colonel Karl Hotz in Nantes, France two days prior brought reprisal deaths of 48 French civilians (mostly communist resistance fighters) with the promise of 50 more deaths if the assassin was not caught. The shooting of a German major in Bordeaux, France brought 100 arrests and 50 immediate executions. ww2dbase [TH]
- Georgy Zhukov took command of Soviet central sector. ww2dbase [Georgy Zhukov | CPC]
- German Panzergruppe 2, resupplied with fuel and ammunition, continued the northeastward advance on Moscow, Russia. German 4th Panzer Division resumed the attack on Mtsensk, Russia. ww2dbase [Battle of Moscow | CPC]
- German submarine U-68 sank British oiler RFA Darkdale off St. Helena in the South Atlantic at 0142 hours, destroying 3,000 tons of fuel oil, 850 tons of aviation fuel, and 500 tons of diesel oil; 41 were killed, 4 survived including the captain. Darkdale was the first British ship to be sunk south of the Equator in WW2. ww2dbase [CPC]
- Marshal Philippe Pétain and Admiral François Darlan broadcast an appeal to the French nation calling restraint from any actions against the occupying German troops which could bring down reprisals on hostages. ww2dbase [Philippe Pétain | AC]
- Prince Takahito married Yuriko Takagi. ww2dbase [Takahito | CPC]

22 Oct 1941 Interactive Map
Timeline Section Founder: Thomas Houlihan
Contributors: Alan Chanter, C. Peter Chen, Thomas Houlihan, Hugh Martyr, David Stubblebine
Special Thanks: Rory Curtis
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